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Select signaling pathways

Welcome.  PathwayLinker identifies and visualizes the first neighbor interactor network of the queried proteins, analyzes the signaling pathway memberships of the proteins in this subnet, and provides links to further online resources.

C. elegans
D. melanogaster
H. sapiens
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Biomedical research often focuses on altering the functions of selected proteins. These changes can unexpectedly perturb signaling pathways and non-specifically affect several cellular processes. PathwayLinker can assist experimental work by linking the queried proteins to signaling pathways through protein-protein and/or genetic interactions.

If you find PathwayLinker useful for your work, interactively or the API, then please cite our work. Thank you.

Linking proteins to signaling pathways for experiment design and evaluation
Farkas I J, Szántó-Várnagy Á, Korcsmáros T
PLoS ONE 7, e36202 (2012)
Abstract  ·  Full Text PDF  ·

Support: European Research Council (FP6-518230 and TAMOP 4.2.1./B-09/1/KMR-2010-0003); Hungarian Scientific Research Fund (K75334); Hungarian Research and Technology Office (5LET-08-2-2009-0041); UCSF Center for Systems and Synthetic Biology (NIGMS P50 GM081879).

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